A clinical trial to compare the efficacy of Ashwagandhadi Ghrita Nasya with Fluticasone Propionate nasal spray in Allergic Rhinitis

Phase 2/3

Not yet recruiting

• Conditions: Other specified respiratory disorders. Ayurveda Condition: VATAJAPRATISYAYAH,

• Registration Number: CTRI/2023/03/050540
• Lead Sponsor: Dr Chiragdip Ranjitsing Deshmukh

Brief Summary

Vataja Pratishyaya (Allergic Rhinitis) is common disease in day to day practice and contemporary science does not have proper solution for treating the same. Around 80% of the patient pool coming to Otorhinolaryngologist belongs to allergic rhinitis. Treatment according to modern science is avoidance of allergens, administration of nasal decongestants, corticosteroids and antihistamines, this may relieve symptoms but may lead to certain side effects. Recurrences are quite common even after treatment. Hence effective management of allergic rhinitis is necessary.

Nasya is the choice of treatment in Ayurveda for Vataja Pratishyaya. Ashwagandhadi Ghrita has ingredients which are found to have anti-inflammatory, analgesic, antioxidant, antihistaminic and antiallergic properties. The study is planned to develop evidence based support for Ashwagandhadi Ghrita nasya in the management of Vataja Pratishyaya .

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-04
• Last Update Posted: 2023-09-03

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patient suffering from Kshawathu( sneezing), Nasa avarodha(nasal congestion), nasa kandu(nasal itching), nasa strava(nasal discharge), shiro gaurav(heaviness in head) and shwasa kashtata( difficulty in breathing).

Exclusion Criteria

• Pregnant and lactating women 2.
• Patients who need surgical and other intervention 3.
• Patients suffering from bacterial or viral rhinitis 4.
• Patients suffering from severe hypertension, malignancy, uncontrolled diabetes mellitus, heart disease and bronchial asthama.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Reduced Sneezing	Enrollment: day 0 | Final follow-up: day 7
2. Improvement in breathing due to clearing of nasal passage.	Enrollment: day 0 | Final follow-up: day 7
3. Reduced Nasal itching.	Enrollment: day 0 | Final follow-up: day 7
4. Reduced Rhinorrhea	Enrollment: day 0 | Final follow-up: day 7
5. Reduced frequency of Headache.	Enrollment: day 0 | Final follow-up: day 7

Secondary Outcome Measures

Name	Time	Method
Improvement in sleep quality	Enrollment: day 0

Trial Locations

Locations (1)

Dr. D. Y. Patil college of Ayurveda and Research centre; 🇮🇳 Pune, MAHARASHTRA, India

Dr. D. Y. Patil college of Ayurveda and Research centre

🇮🇳Pune, MAHARASHTRA, India

Dr Chiragdip Ranjitsing Deshmukh

Principal investigator

7709779541

dchirag8241@gmail.com