remic Toxin Removal and Hemodynamics in Long-Hour Hemodialysis and Hemodiafiltration; A Randomized Cross-Over Study

Completed

• Conditions: end-stage renal disease; 10029149

• Registration Number: NL-OMON38305
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 65

Inclusion Criteria

-prevalent stable CHD patients with insignificant residual urine production
-AV-fistula enabling double-needle vascular access with blood flow rate of at least 350 ml/min
-informed consent
-age more than 18 years

Exclusion Criteria

-withdrawal of consent
-acute intercurrent illness (infection, malignancy, cardiovascular event, uncontrolled diabetes)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome of this study is the removal of (especially protein-bound)<br /><br>uremic toxins. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Microcirculation measured by capillaroscopy</p><br>