A Prospective Cohort of Hainan Community Elderly Population with Cognitive Impairment
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- The prevalence and incidence of cognitive impairment base on the communities
研究概览
简要总结
This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up. The research aims to identify risk factors as well as health and social outcomes that are associated with cognitive impairment in elderly populations, and independently develop AI-assisted software and applications for cognitive enhancement and physical rehabilitation training.
详细描述
This is a community-based prospective cohort study in Hainan Province, China. Subjects are individuals aged 60 years and above who have lived in the communities for more than six months and have signed informed consent. The research have been initialed in 2023 and aims to identify the risk factors associated with cognitive impairment, to develop software for cognitive enhancement and physical rehabilitation training. The study includes three steps: first, to conduct cognitive function screening in 16 communities in four districts (Xiuying, Meilan, Longhua, and Qiongshan) of Haikou City and establish a database for the elderly in tropical regions; second, to identify risk factors associated with cognitive impairment in the elderly population; finally, to independently develop a software for cognitive function enhancement and physical rehabilitation training.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 60 years and above
- •Lived in the community for more than 6 months
- •Signed the informed consent form
排除标准
- •Cannot complete the survey
结局指标
主要结局
The prevalence and incidence of cognitive impairment base on the communities
时间窗: An average of 1 to 2 years
Mild cognitive impairment was measured using a Chinese version Mini-Mental State Examination, which was collected by questionnaire. The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the cognition outcome.
The prevalence and incidence of dementia using a population-based survey
时间窗: An average of 1 to 2 years
Dementia was determined by diagnosis of hospitalization or Clinical Dementia Rating Scale (Montreal Cognitive Assessment, MoCA). The minimum value of the MoCA is 0, and the maximum value is 30, the higher the score, the better the outcome. In addition, subtypes of dementia will be based on the specific clinical diagnosis.
The conversion rate of normal to cognitive impairment
时间窗: An average of 1 to 2 years
Percentage of enrolled population that convert from normal to cognitive impairment
The conversion rate of cognitive impairment to dementia
时间窗: An average of 1 to 2 years
Percentage of enrolled population that convert from cognitive impairment to dementia
次要结局
未报告次要终点
研究者
Jindong Ding Petersen
Professor
Hainan Medical College