Milk Against Respiratory Tract Infections and Asthma

Not Applicable

Conditions: J45
J06
T78.4
Asthma
Acute upper respiratory infections of multiple and unspecified sites
Allergy, unspecified

Registration Number: DRKS00014781

Lead Sponsor: Klinikum der Universität München - Dr. von Haunersches Kinderspital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 260

Inclusion Criteria

Healthy, term-born (35 gestational weeks) infants of both sexes; Age 6 to 12 months at randomization; Caregivers with the ability to follow study instructions and likely to attend and complete all required visits; Caregivers have a mobile phone or a personal computer and are likely to keep a web-based diary regularly; Written informed consent of the parents or guardians

Exclusion Criteria

Suspected or confirmed cow’s milk allergy, milk intolerance, lactose intolerance, suspected immunodeficiency, cystic fibrosis, failure to thrive; Simultaneous participation in another intervention study; Maternal age below 18 years; Uncertainty of the study physician about prospective adherence to study protocol, e.g. known or persistent abuse of medication, drugs or alcohol in caregivers; A sibling already enrolled

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Atopic sensitization at age 3 years

Secondary Outcome Measures

Name	Time	Method
Physician diagnosis of asthma until age 5; Rhinitis irrespective of cough and wheeze until age 3 years; Respiratory tract infections without wheeze until age 3 years; Otitis media until age 3 years; Atopic eczema at age 3 years; Levels of high-sensitivity C-reactive protein in serum at age 3 years