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Clinical Trials/NCT00823914
NCT00823914
Completed
Not Applicable

Developing A Validated Measure of the Impact of Psoriasis on Chronic Quality of Life

Massachusetts General Hospital1 site in 1 country116 target enrollmentDecember 2008
ConditionsPsoriasis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Psoriasis
Sponsor
Massachusetts General Hospital
Enrollment
116
Locations
1
Primary Endpoint
Chronic Quality of Life (CQOL) survey validation.
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

Objective of the study is to create and validate Chronic Quality of Life (CQOL) index that explores habits, career paths and other life choices psoriasis patients make as a result of coping with their disease that may not be impacted by therapy implemented at a given point in time.

  • The investigators think this data will show that patients who were diagnosed at a young age will have worse chronic quality of life.

Detailed Description

As a visible disease, psoriasis can be embarrassing and psychosocially stressful in addition to physically uncomfortable. Patients' lives are affected in physical, psychological, social, sexual and occupational aspects. These burdens may cause patients to assume maladaptive habits and coping mechanisms, leading to a downward spiral in functioning within society, prohibiting patients from achieving their highest potential quality of life. The investigators' study goal is to create and validate Chronic Quality of Life (CQOL) index that explores habits, career paths and other life choices psoriasis patients make as a result of coping with their disease that may not be impacted by therapy implemented at a given point in time. In creating this questionnaire and validating it the investigators will collect preliminary data. The investigators think this data will show that patients who were diagnosed at a young age will have worse chronic quality of life. In the long run, the investigators will use the CQOL index in studies in which patients are treated for psoriasis to determine which treatments can change a psoriasis patient's chronic quality of life. This information will be used to create guidelines for treatment focused on achieving a patient's optimal quality of life. Another aspect that the investigators would like to look at is the skin carotenoid levels in the psoriasis population. Previous studies showed that psoriasis patients had lower levels of skin carotenoids when compared to healthy volunteers. This observation was not statistically significant perhaps due to a small sample size (21 subjects in the psoriasis group and 35 subjects in the control group). Skin carotenoid levels measurement is optional for study subjects.

Registry
clinicaltrials.gov
Start Date
December 2008
End Date
December 2013
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Alexandra Kimball

Principal Investigator

Massachusetts General Hospital

Eligibility Criteria

Inclusion Criteria

  • Able to understand and sign informed consent
  • Able to read English
  • Able to comply with study procedure
  • Male or female of at least 18 years of age
  • Has a diagnosis of psoriasis

Exclusion Criteria

  • Has any medical condition that might interfere with ability to complete CQOL survey

Outcomes

Primary Outcomes

Chronic Quality of Life (CQOL) survey validation.

Time Frame: 1 year

Secondary Outcomes

  • Skin carotenoid levels(1 year)

Study Sites (1)

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