Quality of Preoxygenation in Emergency Surgery

• Conditions: Surgery; Preoxygenation; Anaesthesia; Emergencies

• Registration Number: NCT04070404
• Lead Sponsor: Vilnius University

Brief Summary

Preoxygenation prior to general anaesthesia prolongs safe apnea time. Proper preoxygenation is always a challenge in emergency surgery.

The aim of our study is to estimate problems encountered during preoxygenation, their risk factors and ways of solving them.

Detailed Description

Factors, that are associated with compromised preoxygenation will be determined during our study. Pulse oximetry data and end-tidal oxygen concentration values will be evaluated in association with risk factors for insufficient anaesthesia face mask seal, difficult intubation, preoxygenation techniques used, comorbidities, physical status, hemodynamic and laboratory measures.

Parameters analysed:

* Preoperative: medical history, physical examination, laboratory findings, anthropometric data

* Intraoperative: preoxygenation equipment and method used (defined by anaesthesiologist in charge of the case), oxygenation and haemodynamic values recorded during preoxygenation and induction of anaesthesia, intraoperative laboratory values (if obtained)

Study Timeline

• Study Start: 2019-05-01
• Study First Submitted: 2019-08-23
• Study First Submitted QC: 2019-08-23
• Study First Posted: 2019-08-28
• Status Verified: 2020-10
• Last Update Submitted: 2020-10-08
• Last Update Posted: 2020-10-09
• Primary Completion: 2021-05-01
• Study Completion: 2022-05-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• written informed consent
• patient going for emergency surgery under general anaesthesia
• age > 18 years

Exclusion Criteria

• informed consent refusal
• noneligible for preoxygenation before general anaesthesia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Efficient preoxygenation in preset time	300 seconds	End-tidal oxygen concentration values

Secondary Outcome Measures

Name	Time	Method
Factors influencing preoxygenation quality	300 seconds	Medical history, physical status, lab findings, preoxygenation equipment and method

Trial Locations

Locations (1)

Vilnius University Hospital Santaros Clinics; 🇱🇹 Vilnius, Lithuania