Cross-sectional study on plasma levels of activated protein C and related plasma proteins in Factor V Leiden and Prothrombin Mutation carriers
Completed
- Conditions
- mutations that increase the risk of blood clotsProthrombotic mutations10064477
- Registration Number
- NL-OMON42226
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Population 1: healthy, 18 years or older, thrombophilia carriership (cases).
Population 2: healthy, 18 years or older, pregnant, thrombophilia carriership (cases)
Exclusion Criteria
Medication that influences secondary hemostasis, known risk factors for venous thromboembolism, current pregnancy complications.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Plasma levels of APC and related plasma proteins.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Plasma levels of proteins related to angiogenic pathways. The correlation<br /><br>between the APC plasma levels according to conventional and the novel assay.</p><br>