The effect of NBS powder in treatment of patients with multi-drug resistant tuberculosis

Phase 3

• Conditions: Respiratory tuberculosis.; Respiratory tuberculosis

• Registration Number: IRCT20230116057135N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

Patients with multi-drug resistant tuberculosis
Patients over 18 years old

Exclusion Criteria

The patient's withdrawal from the study
Patients with any other chronic disease such as diabetes, cardiovascular disease, etc.
Patients who have received supplements of vitamin D, zinc, B vitamins and other micronutrients in the last month.
Patients who do not come for follow-up treatment at specified intervals
Pregnant and lactating mothers
Use of corticosteroids and immunosuppressive drugs
Observing any drug sensitivity (especially digestive sensitivity to gluten) as determined by the attending physician
Deterioration of the patient's clinical symptoms due to the consumption of Nutrition Bio-Shield (NBS) powder, as determined by the attending physician
Patient's death during common and selective treatments (in case of death, the patient's information is fully recorded and laboratory tests are performed along with other samples to determine the possible effect of the drug on the patient's death)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Microbial load. Timepoint: Before of the intervention, monthly monitoring, after of the intervention. Method of measurement: Examining the Ziehl–Neelsen staining slide, colony count.;Measurement of white blood cells. Timepoint: Before of the intervention, After of the intervention. Method of measurement: Cell Counter.;Measurement of inflammatory factors. Timepoint: Before of the intervention, After of the intervention. Method of measurement: Gold Standard Methods (Westergren method for ESR, Electrochemical Immunoassay for CRP).