The Circadian Rhythm of Copeptin

Completed

• Conditions: Circadian Rhythm; Copeptin Blood Levels
• Interventions: Other: observation

• Registration Number: NCT02604875
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

The circadian rhythm of copeptin will be examined in healthy subjects.

Detailed Description

In 18 healthy volunteers the circadian rhythm of copeptin will be examined by withdrawing blood samples for copeptin levels every 30 minutes for 24 hours.

Study Timeline

• Study Start: 2015-11
• Study First Submitted: 2015-11-10
• Study First Submitted QC: 2015-11-13
• Study First Posted: 2015-11-16
• Primary Completion: 2016-04
• Study Completion: 2016-04
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-12
• Last Update Posted: 2016-08-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• healthy subjects

Exclusion Criteria

• acute illness
• chronic illness
• pregnancy
• Anemia defined as Hb < 30g/l

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
observational	observation	Blood samples will be taken for measuring copeptin levels in healthy subjects.

Primary Outcome Measures

Name	Time	Method
measurement of copeptin values in mmol/l within 24 hours to assess the amount of release in a day curve.	24 hours	The primary outcome measure is to compare the copeptin concentration in the early afternoon and the early morning by blood sampling at different time points. Evaluation of the question if there is a circadian rhythm in the copeptin release.

Trial Locations

Locations (1)

University Hospital Basel; 🇨🇭 Basel, Basel-Stadt, Switzerland