Comparison of blood pressure lowering effect of amlodipine between once-a-daily administration and twice-a-daily administratio
Not Applicable
- Conditions
- Essential hypertension
- Registration Number
- JPRN-UMIN000003914
- Lead Sponsor
- Department of Integrated Medicine and Infomatics, Ehime University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients with secondary hypertension 2. Patients with SBP 150 mmHg or greater,or DBP 100 mmHg or greater. 3. Patients with malignant hypertension 4. Patients who were hospitalized because of stroke, myocadial infarction or vascular diseases within 6 months. 5. Patients with atrial fibrillation. 6. Patients with elevated liver enzymes. (AST or ALT is more than 2.5 times as high as upper normal limit) 7. Patients with elevated serum creatinine (2.0mg/dL or greater) 8. Pregnant or nursing women 9. Patients who are considered as inappropriate to participants for this study by attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in 24 h mean blood pressure between the treatment with amlodipine 10mg once a daily and amlodipine 5mg twice a daily
- Secondary Outcome Measures
Name Time Method