Clinical Pregnancy Rate in Women With Unexplained Infertility After Removal of Unsuspected Intrauterine Pathology
Overview
- Phase
- Phase 3
- Intervention
- polypectomy
- Conditions
- Infertility
- Sponsor
- Karachi Medical and Dental College
- Primary Endpoint
- Clinical pregnancy rate:
- Status
- Withdrawn
- Last Updated
- 7 years ago
Overview
Brief Summary
Polyps are fleshy outgrowths of the inner lining of the womb which may hinder implantation of embryo and lead to subfertility.This study evaluates whether removal of endometrial polyps in womb affects chances of pregnancy in women in whom no other causes of subfertility can be found. Half of the women would have these polyps removed after their consent and the other half who would not consent would not undergo any such intervention
Investigators
samia husain
research assistant
Karachi Medical and Dental College
Eligibility Criteria
Inclusion Criteria
- •Normal semen analysis
- •24 months of unprotected sexual intercourse
- •NORMAL TVS
- •Normal hysterosalpingogram
- •Evidence of spontaneous ovulation
- •No history of Pelvic inflammatory disease
- •Polyps on saline sonography
Exclusion Criteria
- •History of taking hormones
- •Thyroid disorder
- •prior hysteroscopy treatment
- •intermenstrual blood loss.
Arms & Interventions
intervention
All women would undergo saline sonography with normal saline. Women with endometrial polyps who consent to the removal of polyps will be offered polypectomy
Intervention: polypectomy
intervention
All women would undergo saline sonography with normal saline. Women with endometrial polyps who consent to the removal of polyps will be offered polypectomy
Intervention: saline sonography
intervention
All women would undergo saline sonography with normal saline. Women with endometrial polyps who consent to the removal of polyps will be offered polypectomy
Intervention: normal saline
control
All women would undergo saline sonography with normal saline. Women with endometrial polyps who do not consent to the removal would serve as controls
Intervention: saline sonography
control
All women would undergo saline sonography with normal saline. Women with endometrial polyps who do not consent to the removal would serve as controls
Intervention: normal saline
Outcomes
Primary Outcomes
Clinical pregnancy rate:
Time Frame: 12 months
number of women who get pregnancy test positive within 12 months of intervention