Clinical Pregnancy Rate in Women With Unexplained Infertility After Removal of Unsuspected Intrauterine Pathology
试验速览
- 阶段
- 3 期
- 状态
- 撤回
- 发起方
- 主要终点
- Clinical pregnancy rate:
研究概览
简要总结
Polyps are fleshy outgrowths of the inner lining of the womb which may hinder implantation of embryo and lead to subfertility.This study evaluates whether removal of endometrial polyps in womb affects chances of pregnancy in women in whom no other causes of subfertility can be found. Half of the women would have these polyps removed after their consent and the other half who would not consent would not undergo any such intervention
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Normal semen analysis
- •24 months of unprotected sexual intercourse
- •NORMAL TVS
- •Normal hysterosalpingogram
- •Evidence of spontaneous ovulation
- •No history of Pelvic inflammatory disease
- •Polyps on saline sonography
排除标准
- •History of taking hormones
- •Thyroid disorder
- •prior hysteroscopy treatment
- •intermenstrual blood loss.
研究组 & 干预措施
intervention
All women would undergo saline sonography with normal saline. Women with endometrial polyps who consent to the removal of polyps will be offered polypectomy
干预措施: polypectomy (Procedure)
intervention
All women would undergo saline sonography with normal saline. Women with endometrial polyps who consent to the removal of polyps will be offered polypectomy
干预措施: saline sonography (Procedure)
intervention
All women would undergo saline sonography with normal saline. Women with endometrial polyps who consent to the removal of polyps will be offered polypectomy
干预措施: normal saline (Drug)
control
All women would undergo saline sonography with normal saline. Women with endometrial polyps who do not consent to the removal would serve as controls
干预措施: saline sonography (Procedure)
control
All women would undergo saline sonography with normal saline. Women with endometrial polyps who do not consent to the removal would serve as controls
干预措施: normal saline (Drug)
结局指标
主要结局
Clinical pregnancy rate:
时间窗: 12 months
number of women who get pregnancy test positive within 12 months of intervention
次要结局
未报告次要终点
研究者
samia husain
research assistant
Karachi Medical and Dental College