Evaluation of Ovarian Reserve in Women With Subclinical Hypothyrodism in Reproductive Age
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Measure the association of SCH with ovarian reserve markers (basal FSH ,LH/basal AFC /AMH)
研究概览
简要总结
This study aimed to evaluate the potential association of subclinical hypothyrodism and ovarian reserve in reproductive age in age groups more than 35 and age groups less than 35 using retrospective study included women with subclinical hypothyrodism and controls .Evaluation of potential association of antithyroid antibodies positivity on ovarian reserve
Primary outcome:
Measure the association of SCH with ovarian reserve markers (basal FSH ,LH/basal AFC /AMH)
详细描述
Thyroid dysfunction is one of the commonest disorders in women of reproductive age .there is association between subclinical hypothyrodism and infertility and ovarian reserve .It's known that subclinical hypothyrodism can be associated with reduced ovarian reserve in women more than 35 years old .Aclear association between subclinical hypothyrodism and ovarian reserve not established in reproductive age in women less than 35 .This retrospective study investigate serum thyroid hormone /Antithyroid hormone ,ovarian reserve markers (basal FSH,AMH,Antral follicle count on day 2-4/prolactin level .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 13 Years 至 45 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All reproductive age groups included women less than 35 and women more than 35
排除标准
- •Previous ovarian surgery Women with long term thyroid hormone replacement Endometriosis History of radiotheraby
结局指标
主要结局
Measure the association of SCH with ovarian reserve markers (basal FSH ,LH/basal AFC /AMH)
时间窗: 48 months
This study aimed to evaluate the potential association of subclinical hypothyrodism and ovarian reserve in reproductive age in age groups more than 35 and age groups less than 35 using retrospective study included women with subclinical hypothyrodism and controls .Evaluation of potential association of antithyroid antibodies positivity on ovarian reserve
次要结局
未报告次要终点
研究者
Eman Ahmed Abed Eltawaab Abdo
Principal Investigator
Assiut University