Fibersol-2 Clinical Trials Related to Appetite
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Visual analog scale questionnaire subjective satiety responses
研究概览
简要总结
Emerging research suggests fiber, particularly digestion-resistant maltodextrins such as Fibersol-2, may impact satiety, by decreasing hunger, prolonging satiation, and/or increasing satiety signals from the gut. This research aims to determine whether or not Fibersol-2 may impact satiety, by decreasing hunger, prolonging satiation, and/or increasing satiety signals from the gut.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 62 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •i. No known food allergies
- •ii. Normal healthy individuals
- •iii. No food intake abnormalities or abnormal feeding behaviors
- •iv. Average American BMI (21-28)
排除标准
- 未提供
结局指标
主要结局
Visual analog scale questionnaire subjective satiety responses
时间窗: 4 hours
Hunger survey (30 minutes before meal and every half hour for 4 hours postprandial) (analogue scores)
serum cholecystokinin (CCK)
时间窗: 4 hours
0, 30, 60, 120, 180, and 240 min post-meal
serum peptide YY (PYY)
时间窗: 4 hours
0, 30, 60, 120, 180, and 240 min post-meal
serum glucagon-like peptide-1 (GLP-1)
时间窗: 4 hours
0, 30, 60, 120, 180, and 240 min post-meal
serum ghrelin
时间窗: 4 hours
0, 30, 60, 120, 180, and 240 min post-meal
serum gastric inhibitory peptide (GIP)
时间窗: 4 hours
0, 30, 60, 120, 180, and 240 min post-meal
次要结局
- serum total cholesterol(4 hours)
- serum LDL-cholesterol(4 hours)
- serum HDL-cholesterol(4 hours)
- serum triglycerides(4 hours)
- serum free fatty acids(4 hours)
- serum glucose(2 hours)
- serum insulin(2 hours)
- gastrointestinal symptoms questionnaire(24 h)