Dexamethasone implant in the treatment of central serous chorioretinopathy
Not Applicable
- Conditions
- Health Condition 1: H357- Separation of retinal layers
- Registration Number
- CTRI/2022/01/039632
- Lead Sponsor
- Hyderabad Eye Research Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients with non-resolving and recurrent CSCR with focal, multifocal, or diffuse leaks on FA
2. Eyes with focal leaks within 1000microns of the center of fovea in chronic CSCR
3. Best corrected vision score of 73 to 34 at test distance of 4 meters on ETDRS chart at recruitment (Snellen equivalent 20/40 to 20/200)
4. Decrease in vision primarily secondary to CSCR
5. Willing to sign informed consent form
Exclusion Criteria
1. Laser or pharmacological treatment for CSCR in previous six months
2. Eyes with choroidal neovascularization demonstrated on OCTA/FA/ICGA
3. Fellow eye vision worse than 20/200
4. Aphakia
5. Patients with glaucoma.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete resolution of SRF as determined on OCT <br/ ><br>The disappearance of intraretinal cystoid spaces <br/ ><br>Visual acuity change <br/ ><br>Change in contrast sensitivity <br/ ><br>Change in mfERG waveforms <br/ ><br>Change in intraocular pressure <br/ ><br>Timepoint: 6 and 12 weeks
- Secondary Outcome Measures
Name Time Method Reappearance of disease <br/ ><br>% Requiring retreatment <br/ ><br>Changes in PED height <br/ ><br>Lens changes <br/ ><br>% Requiring medical/surgical treatment for glaucoma <br/ ><br>Timepoint: 3,6,9 and 12 months