Dietary effects of culinary herbs and spices on body weight in patients on antidepressants and antipsychotics

Not Applicable

• Conditions: Obesity; Depression; Diet and Nutrition - Obesity; Mental Health - Depression

• Registration Number: ACTRN12617000270314
• Lead Sponsor: a Trobe University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-02-22
• Last Update Posted: 3 March 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

Groups that require participants on antidepressants:
1- Age range: 18-54 years
2- People who are diagnosed with depression and are currently on prescribed antidepressants.

Group that requires non-depressed participants:
1- Age range: 18-54 years
2- Healthy over-weight participants who their BMI is between 25-30

Exclusion Criteria

Those who are highly dependent on medical care, people with a cognitive impairment, intellectual disability, mental illness, non-English speaking (to ensure ethical consent) will be excluded from the study. People diagnosed with a chronic heart failure, chronic inflammatory disease will be excluded as well due to increased risk and likelihood of medical issues that could affect the result of the study. Women who are currently breastfeeding or pregnant will be excluded as well. People who are currently participating in a similar intervention and those who are unable to attend the appointment (data collection requires physical presence) will be excluded from this study. People who are taking any medication that could cause weight gain will be excluded except antidepressants.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in body fat assessed using DEXA scan,[1-Baseline<br>2- Four weeks after intervention commencement<br>3- Eight weeks after intervention commencement<br>4- Twelve weeks weeks after intervention commencement];Change in body weight assessed using a weight scale[1-Baseline<br>2- Four weeks after intervention commencement<br>3- Eight weeks after intervention commencement<br>4- Twelve weeks weeks after intervention commencement]

Secondary Outcome Measures

Name	Time	Method
Change in depression levels assessed using SCID-5[1-Baseline<br>2- Four weeks after intervention commencement<br>3- Eight weeks after intervention commencement<br>4- Twelve weeks weeks after intervention commencement];Change in C-reactive protein levels assessed using blood samples[1-Baseline<br>2- Four weeks after intervention commencement<br>3- Eight weeks after intervention commencement<br>4- Twelve weeks weeks after intervention commencement]