Efficacy of Ketorolac IV Versus wound instillation for post operative analgesia following thyroidectomy
Not Applicable
- Conditions
- Health Condition 1: E079- Disorder of thyroid, unspecified
- Registration Number
- CTRI/2019/04/018438
- Lead Sponsor
- IZAMS INSTITUTE OF MEDICAL SCIENCES
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients aged between 18 to 60 years of ASA physical status I and II with informed written consent posted for elective thyroid surgeries will be included in the study.
Exclusion Criteria
Patient refusal
-GI bleeding disorder
- Allergy or sensitive to ketorolac, aspirin, or other NSAID
- Severe Cardiac,Renal, Hepatic insufficiency
- Coagulopathy, Severe bronchial asthma.
-Radiotherapy
-Previous analgesic and anti inflammatory treatment.
-Neurological alteration.
- Pregnancy n lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Primary outcome of this study will be the efficacy of I V ketorolac vs wound instillation with ketorolac on reducing post operative pain using VAS score in post operative patients for thyroid surgery and requirement of rescue analgesics along with haemodynamic changes and anxiety.0,4,12,24hrsTimepoint: 24hrs
- Secondary Outcome Measures
Name Time Method Incidence of side effects including nausea, vomiting shivering post op bleeding. <br/ ><br>Incidence of nausea and vomiting estimated at 0,4 ,12 and 24hrs <br/ ><br>For severe nausea and episodes of vomiting , I V administration of ondansetron 4mg will be given as a rescue anti emetic. <br/ ><br>Timepoint: 24hrs