Review of Kidney Biopsies of Dent Disease Patients
- Conditions
- Dent Disease
- Interventions
- Procedure: Renal Biopsy
- Registration Number
- NCT02022189
- Lead Sponsor
- Mayo Clinic
- Brief Summary
This study is being done to obtain pathology reports from all patients in the Dent disease registry who have had a kidney biopsy. The investigator will collect the biopsy slides and reports in an attempt to determine if they have any common findings.
- Detailed Description
If the patient agrees to be in the study, the patient will be asked to participate in the following:
* Sign a consent form indicating the patient's willingness to participate.
* Provide a signed medical release form allowing the investigator to request your official kidney biopsy reports, and also allowing the investigator to request the original slides for review. At the end of the study, all slides will be returned to the referring facility.
* The investigator will also review your medical record
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 20
- All patients in the Dent Disease Registry with a previous renal biopsy.
- None.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Dent Disease patients Renal Biopsy Patients with diagnosed Dent Disease
- Primary Outcome Measures
Name Time Method Biopsy changes 2 years The primary outcome will be to determine the number of glomeruli, percent globally sclerotic glomeruli, percent focally sclerotic glomeruli, and the severity of interstitial fibrosis (none, mild, moderate, severe) and interstitial crystals (none, mild, moderate, severe)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mayo Clinic
🇺🇸Rochester, Minnesota, United States