A study on antibiotic use to prevent infections after miscarriage
Phase 4
Recruiting
- Conditions
- Incomplete and missed miscarriage
- Registration Number
- SLCTR/2014/010
- Lead Sponsor
- niversity Obstetrics and Gynaecology Unit,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Woman who present to ward NO: 03, T.H .Peradeniya (Gynaecology Professorial Unit) with incomplete and missed miscarriage diagnosed by Trans vaginal ultrasound as below:
1. Incomplete miscarriage: thickness of products of conception is > 1.5 cm
2. Missed miscarriage: Gestational sac >25mm without fetal pole or fetal pole CRL> 7mm without heart beat
Exclusion Criteria
1. Signs and symptoms of infection including
• Temperature > 37 0C
• Lower abdominal tenderness
• Offensive vaginal discharge
• Cervical excitation
2. Known allergy to doxycycline
3. POG=/< than 24 weeks.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical signs of infection (at least 3 of the following)<br><br>1. In the history: fever, chills, headache, lower abdominal pain and smelly vaginal discharge.<br>2. Temperature >37 degrees C.<br>3. Lower abdominal tenderness.<br>4. Positive cervical excitation test with or without adenexial tenderness.<br>5. Presence of smelly vaginal discharge.<br> [At completion of three days and at 2 weeks post intervention]<br>
- Secondary Outcome Measures
Name Time Method one [None]<br>