Donpezil efficacy in prevention of cognitive impairment induced by electroconvulsivetherapy
Phase 3
- Conditions
- Cognitive impairment.
- Registration Number
- IRCT20180623040193N1
- Lead Sponsor
- Shahre-kord University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 94
Inclusion Criteria
Age 15-65 years old
Diagnosis of Major depressive disorder by a psychiatrist
Diagnosis of bipolar disorder by a psychiatrist
Prescribing at least four session of elecctroconvulsivetherapy
inform consent
Exclusion Criteria
Dissatisfaction for continued study
Mental retardation
dementia
discontinue treatment before session 4
Delirium during treatment
Prohibition of acetyl cholinesterase inhibitors because of a cardiac disorder
chronic obstructive pulmonary disease
Acute peptic ulcer
Lack of literacy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive impairment. Timepoint: before start of electroconvulsivetherapy, before session 4 and one month after the end of electroconvulsivetherapy. Method of measurement: Addenbrooke’s Cognitive Examination-C, mini mental status examination.
- Secondary Outcome Measures
Name Time Method