Endometriosis and Brominated Flame Retardant (ENDOTOX Study)

Completed

• Conditions: Endometriosis

• Registration Number: NCT02651077
• Lead Sponsor: Nantes University Hospital

Brief Summary

The investigators wish to highlight, in a Case-Control design, if there is an increased concentration of BFRs in omental adipose tissue of cases ( women with severe endometriosis with surgical indication ) versus bioaccumulation recorded in a control cohort ( women recruited in obstetrics and gynecology or visceral surgery showing no sign of endometriosis ) . Pairing will be operate on Age (+/- 5 years compared to the case ) , BMI ( BMI 5 Classes described by the HAS) and previous breastfeeding experience (yes / no , opposite the release expected bioaccumulate contaminants in breast adipose tissue , when the lactation ) .

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11
• Primary Completion: 2014-11
• Study Completion: 2014-11
• Status Verified: 2016-01
• Study First Submitted: 2016-01-06
• Study First Submitted QC: 2016-01-07
• Last Update Submitted: 2016-01-07
• Study First Posted: 2016-01-08
• Last Update Posted: 2016-01-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 76

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concentrations of brominated flame retardant (BFR) in adipose tissue and serum	baseline

Secondary Outcome Measures

Name	Time	Method
Concentrations of dioxins in adipose tissue and serum	baseline
Concentrations of polychlorinated biphenyls (PCBs),	baseline
Concentrations of organochlorine pesticides (OCPs) in adipose tissue and serum	baseline

Trial Locations

Locations (1)

Nantes University Hospital; 🇫🇷 Nantes, France