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临床试验/NCT02651077
NCT02651077已完成不适用

Looking for a Link Between Endometriosis and Exposure to Lipophilic Environmental Chemicals Like Brominated Flame Retardant (ENDOTOX Study)

Nantes University Hospital1 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2013年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
76
试验地点
1
主要终点
Concentrations of brominated flame retardant (BFR) in adipose tissue and serum

研究概览

简要总结

The investigators wish to highlight, in a Case-Control design, if there is an increased concentration of BFRs in omental adipose tissue of cases ( women with severe endometriosis with surgical indication ) versus bioaccumulation recorded in a control cohort ( women recruited in obstetrics and gynecology or visceral surgery showing no sign of endometriosis ) . Pairing will be operate on Age (+/- 5 years compared to the case ) , BMI ( BMI 5 Classes described by the HAS) and previous breastfeeding experience (yes / no , opposite the release expected bioaccumulate contaminants in breast adipose tissue , when the lactation ) .

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Concentrations of brominated flame retardant (BFR) in adipose tissue and serum

时间窗: baseline

次要结局

  • Concentrations of dioxins in adipose tissue and serum(baseline)
  • Concentrations of polychlorinated biphenyls (PCBs),(baseline)
  • Concentrations of organochlorine pesticides (OCPs) in adipose tissue and serum(baseline)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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