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Clinical Trials/NCT02651077
NCT02651077
Completed
Not Applicable

Looking for a Link Between Endometriosis and Exposure to Lipophilic Environmental Chemicals Like Brominated Flame Retardant (ENDOTOX Study)

Nantes University Hospital1 site in 1 country76 target enrollmentNovember 2013
ConditionsEndometriosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Endometriosis
Sponsor
Nantes University Hospital
Enrollment
76
Locations
1
Primary Endpoint
Concentrations of brominated flame retardant (BFR) in adipose tissue and serum
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The investigators wish to highlight, in a Case-Control design, if there is an increased concentration of BFRs in omental adipose tissue of cases ( women with severe endometriosis with surgical indication ) versus bioaccumulation recorded in a control cohort ( women recruited in obstetrics and gynecology or visceral surgery showing no sign of endometriosis ) . Pairing will be operate on Age (+/- 5 years compared to the case ) , BMI ( BMI 5 Classes described by the HAS) and previous breastfeeding experience (yes / no , opposite the release expected bioaccumulate contaminants in breast adipose tissue , when the lactation ) .

Registry
clinicaltrials.gov
Start Date
November 2013
End Date
November 2014
Last Updated
10 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Concentrations of brominated flame retardant (BFR) in adipose tissue and serum

Time Frame: baseline

Secondary Outcomes

  • Concentrations of dioxins in adipose tissue and serum(baseline)
  • Concentrations of polychlorinated biphenyls (PCBs),(baseline)
  • Concentrations of organochlorine pesticides (OCPs) in adipose tissue and serum(baseline)

Study Sites (1)

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