Looking for a Link Between Endometriosis and Exposure to Lipophilic Environmental Chemicals Like Brominated Flame Retardant (ENDOTOX Study)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endometriosis
- Sponsor
- Nantes University Hospital
- Enrollment
- 76
- Locations
- 1
- Primary Endpoint
- Concentrations of brominated flame retardant (BFR) in adipose tissue and serum
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The investigators wish to highlight, in a Case-Control design, if there is an increased concentration of BFRs in omental adipose tissue of cases ( women with severe endometriosis with surgical indication ) versus bioaccumulation recorded in a control cohort ( women recruited in obstetrics and gynecology or visceral surgery showing no sign of endometriosis ) . Pairing will be operate on Age (+/- 5 years compared to the case ) , BMI ( BMI 5 Classes described by the HAS) and previous breastfeeding experience (yes / no , opposite the release expected bioaccumulate contaminants in breast adipose tissue , when the lactation ) .
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Concentrations of brominated flame retardant (BFR) in adipose tissue and serum
Time Frame: baseline
Secondary Outcomes
- Concentrations of dioxins in adipose tissue and serum(baseline)
- Concentrations of polychlorinated biphenyls (PCBs),(baseline)
- Concentrations of organochlorine pesticides (OCPs) in adipose tissue and serum(baseline)