A CLINICAL TRIAL TO STUDY THE EFFECTS OF HYPERBARIC BUPIVACAINE AND FENTANYL DRUGS GIVEN EITHER AS A MIXTURE OR SEQUENTIALLY FOR SPINAL ANAESTHESIA IN PATIENTS UNDERGOING CAESAREAN SECTIO
Phase 1
- Conditions
- Health Condition 1: null- Adult ASA I,II parturients with height 145-165 cm and Body mass index 35 kg/m2
- Registration Number
- CTRI/2018/03/012602
- Lead Sponsor
- Vardhman Mahavir Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult ASA physical status I, II with height 145-165 cm and Body mass index (BMI) < 35 kg/m2
Exclusion Criteria
Known coagulation abnormality or bleeding diathesis, local infection at the site of spinal injection, raised intracranial tension, chronic hypertension, severe hypotension, hypovolaemia, cord prolapse, hypersensitivity to local anaesthetic or fentanyl.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the efficacy of hyperbaric bupivacaine and fentanyl given either as a mixture or sequentially for subarachnoid block in terms of 1) Block characteristics, 2) Haemodynamic parameters 3) Time required to achieve sensory block height (T5) for caesarean section.Timepoint: Before giving surgical incision
- Secondary Outcome Measures
Name Time Method To evaluate the duration of sensory and motor block, total dose of vasopressor and neonatal outcome as assessed by Umbilical cord blood gas analysis, Apgar Score and need for Neonatal Resuscitation in above patientsTimepoint: at the time of giving subarachnoid block, during surgery and post operative period