UNC Pleural Fluid Registry

Recruiting

• Conditions: Breast Cancer; Empyema; Malignant Pleural Effusion; Lung Cancer; Lung Infection

• Registration Number: NCT05620329
• Lead Sponsor: UNC Lineberger Comprehensive Cancer Center

Brief Summary

Research with biospecimens such as blood, tissue, or body fluids can help researchers understand how the human body works. Researchers can make new tests to find diseases, understand how treatments work, or find new ways to treat a disease. The purpose of this study is to collect biospecimens for research from patients with known or suspected lung cancer. The information learned from the biospecimens may be used in future treatments. The purpose of this protocol is to create a pleural fluid registry for use in future studies.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-24
• Study First Submitted: 2022-11-09
• Study First Submitted QC: 2022-11-09
• Study First Posted: 2022-11-17
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-10
• Last Update Posted: 2024-10-14
• Primary Completion: 2050-01-24
• Study Completion: 2050-01-24

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 9999

Inclusion Criteria

• Patients who are 18 years or older
• Inpatients and outpatients
• Diagnosed with pleural fluid, are referred for and undergo clinically indicated drainage who have clinical evidence of:
• pulmonary infection (such as fever, leukocytosis, new or worsening infiltrate on chest x-ray, or clinical deterioration) with effusion
• malignancy

Read More

Exclusion Criteria

• A subject will not be eligible for inclusion in this registry if, in the investigator's (or treating clinician's) opinion, the patient has any concurrent medical condition that may preclude their ability to undergo pleural fluid drainage safely.
• Incarcerated individuals

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Creation of a pleural fluid registry	32 years	Biological specimens and corresponding clinical data from subjects will be collected during standard of care procedures and medical record abstraction to support the creation of a pleural fluid registry.

Trial Locations

Locations (1)

UNC Lingeberger Comprehensive Cancer Center; 🇺🇸 Chapel Hill, North Carolina, United States