MedPath

Observation of Atelectasis Using Lung Ultrasonography in Children Undergoing General Anesthesia: the Cohort Study for Evaluation of the Relationship Between the Incidence and Severity of Upper Respiratory Tract Infection and the Magnitude of Anesthesia-induced Atelectasis

Completed
Conditions
Surgery
Interventions
Other: questionnaire about the severity of their symptoms of upper respiratory tract infection
Registration Number
NCT03355547
Lead Sponsor
Yonsei University
Brief Summary

Pediatric patients between 6months and 6years old will be included. They are scheduled for elective general or urologic surgery at a single tertiary medical center. Before the operation, the researcher interviews the parents of the pediatric patients to check whether they have the upper respiratory tract infection and asks them to fill out a questionnaire about the severity of their symptoms. The researcher will get the symptom score of the upper respiratory tract infection in the questionnaire. The degree of anesthesia induced atelectasis is measured using lung ultrasound. Pulmonary ultrasound is performed after endotracheal intubation and at the end of the operation dividing the patient's thorax into 12 regions. The investigator grades the degree of atelectasis at each region form 0 to 3 points. After the end of the operation, check whether the respiratory adverse effects occurred during emergence and recovery at the post anesthesia care unit.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
261
Inclusion Criteria
  • Age: Pediatric patients older than 6 months and younger than 6 years
  • scheduled for elective pediatric general or urology surgery.
Read More
Exclusion Criteria
  • undergoing laparoscopic surgery
  • pediatric patients with lower respiratory tract infection( pneumonia , bronchiolitis )
  • patients with bronchopulmonary dysplasia history
  • hemodynamic instability
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
no URI (upper respiratory tract infection) symptomsquestionnaire about the severity of their symptoms of upper respiratory tract infectionPatients without upper respiratory tract infection symptoms
URI (upper respiratory tract infection) symptomsquestionnaire about the severity of their symptoms of upper respiratory tract infectionPatients with upper respiratory tract infection symptoms
Primary Outcome Measures
NameTimeMethod
The degree of atelectasis due to general anesthesia using lung ultrasoundThe investigator will measure the degree of atelectasis using lung ultrasound at 2 minutes after endotracheal intubation and at 5minutes the end of the operation.

Anesthesia induced atelectasis is diagnosed when the ultrasound findings as B-line (appears hyperechoic lines perpendicular to the pleura) and consolidation(loss of pleural line and hypoechoic area) are identified. The chest is divided into 12 regions: three longitudinal lines (parasternal, anterior, and posterior axillary) and two axial lines (above the diaphragm, and 1cm above the nipples) in each hemithorax. The investigator grades the degree of atelectasis at each region form 0 to 3 points. The degree of juxtapleural consolidation was graded: (a0) no consolidation; (a1) minimal juxtapleural consolidation; (a2) small-sized consolidation(\<50%); and (a3) large-sized consolidation(\>50%). The degree of B-lines was divided into four grades: (b0) fewer than three isolated B-lines; (b1) multiple well-defined B-lines; (b2) multiple coalescent B-lines; and (b3) white lung.

Secondary Outcome Measures
NameTimeMethod
Occurrence of respiratory adverse effects after the operation30 minutes after extubation at the post anesthesia care unit

After the end of the operation, check whether the respiratory adverse effects occurred when the patient is extubated and 10, 30 minutes after extubation at the post anesthesia care unit. Respiratory adverse effects are bronchospasm and laryngospasm. We analyze the symptom score of upper respiratory tract infection in pediatric patients who showed respiratory adverse events and suggest the cut off value of the score with high risk of respiratory adverse events by multivariate logistic regression.

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine Anesthesia and Pain Research Institute Yonsei University College of Medicine

🇰🇷

Seoul, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath