Intravenous Paracetamol Versus Intravenous Dexketoprofen in Patients Presented With Dysmenorrhea in Emergency Department
试验速览
- 阶段
- 4 期
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Visual Analogue Scale
研究概览
简要总结
Patients presented with dysmenorrhea composed the study population. One gram paracetamol and 50 mg dexketoprofen in 100 ml saline with a rapid infusion were compared in ceasing dysmenorrhea in emergency department.
详细描述
Patients over 18 years old who presented with dysmenorrhea composed the study population. Patients received pain killer within the last six hours, physical findings consistent with peritoneal irritation, allergy to the study drugs, renal or liver failure, drug addiction, pregnancy or woman with lactation and denied to give inform consent were the exclusion criteria. The pain of the study patients are measured with visual analogue scale at baseline, 15th and 30th minutes. At the end of the 30 minutes, rescue drug need is also recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients with dysmenorrhea
- •Patients over 18 years old
排除标准
- •denied to give inform consent
- •Renal or liver failure
- •Allergy to the study drugs
- •Receiving pain killer within the last 6 hours.
- •Physical examination findings consistent with peritoneal irritation
- •Pregnancy or patients with lactation
- •Drug addiction
研究组 & 干预措施
Paracetamol
Intravenous 1 gm paracetamol in 100 ml saline with rapid infusion
干预措施: Paracetamol (Drug)
Dexketoprofen
Intravenous 50 mg dexketoprofen in 100 ml saline with rapid infusion
干预措施: Dexketoprofen (Drug)
结局指标
主要结局
Visual Analogue Scale
时间窗: 30 minutes
Change in visual analogue scale at 30th minutes from baseline
次要结局
- Rescue drug need(30 minutes)
- Adverse effects(30 minutes)
研究者
Cenker Eken
Associate Professor
Akdeniz University