Treatment of chronically inflamed knee joints with aspiration and corticosteroid injectio

Phase 4

• Conditions: Inflammatory arthritis of the knee joint; Inflammatory and Immune System - Rheumatoid arthritis; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12608000127303
• Lead Sponsor: AUT University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-03-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. A primary diagnosis of inflammatory arthritis, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, crystal arthritis.
2. A clinically detectable knee joint effusion as well as other clinical signs and symptoms of knee joint synovitis including pain on motion, heat and tenderness on palpation.

Exclusion Criteria

1.Recent history of an intra-articular corticosteroid injection to the knee joint.
2.Any medical condition that may preclude the performance of maximum effort strength tests.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quadriceps muscle function - peak isometric torque, electromyography (EMG) amplitude and muscle fibre conduction velocity[Baseline, post aspiration, 4 days post intervention, 2 weeks post intervention];Lower limb function - self report questionnaires, 10 metre walk test, 6 minute walk test.[Baseline, 4 days post intervention, 2 weeks post intervention];Flexion reflex excitability - threshold, Area under the curve at 1.2 x threshold[Baseline, post aspiration, 4 days post intervention, 2 weeks post intervention]

Secondary Outcome Measures

Name	Time	Method
Pain - Visual analogue scale (VAS)[Baseline, 4 days post intervention, 2 weeks post intervention]