Effect of acupotomy on improving knee joint function and regulating perigenicular EMG signal in patients with moderate to severe KOA

Phase 1

• Conditions: knee osteoarthritis

• Registration Number: ITMCTR2200006691
• Lead Sponsor: School of Acupuncture and Massage, Beijing University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

? Meet the diagnostic standards of Western medicine;
? Imaging conforms to Kellgren-Lawrence grades III-IV;
? It belongs to medial compartment knee osteoarthritis, pain in the medial knee, narrowing of the medial compartment, and the imaging manifestations of the affected knee joint meet the standards of knee varus (tibiofemoral angle > 175 °);
? VAS = 4 points;
? BMI < 30;
? Those aged 40-70;
? The subjects have no experience in knee acupuncture treatment and can receive acupuncture treatment;
? Subjects who signed an informed consent form, voluntarily participated in this study, had good compliance, and did not withdraw midway.

Exclusion Criteria

? Osteoarthritis caused by rheumatoid arthritis, rheumatoid arthritis, gouty arthritis, psoriatic arthritis, hemophiliac arthritis, ankylosing spondylitis, osteomyelitis, bone tumor and bone tuberculosis, as well as lateral compartment type, patellar type, total articular knee osteoarthritis;
? Other diseases that may affect knee osteoarthritis, such as psoriasis, acute trauma, syphilis, diabetes, etc.;
? Lower extremity pain or dysfunction caused by non-knee diseases;
? Subjects who are not suitable for acupuncture, such as skin damage, ulceration, local infection, history or clinical manifestations of bleeding tendency (including those currently using anticoagulants);
? Pregnant or breastfeeding subjects;
? Mental, intellectual disabilities, etc., subjects who are difficult to cooperate with treatment;
? Those with impaired heart, liver, kidney and respiratory functions or other serious diseases of various systems;
? Those who are allergic to isopropanol, propylene glycol or other non-steroidal anti-inflammatory drugs.
? Observers who have received other related treatments that may affect the effect indicators of this study;

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Joint range of motion;Visual Analogue Scale;The Western Ontario and McMaster Universities Osteoarthritis Index;

Secondary Outcome Measures

Name	Time	Method
Soft tissue tension;myodynamia;Force;surface electromyogram signal;The lower limb skin temperature;pressing pain;