Het effect van coblatie behandeling op kraakbeen kwaliteit
- Conditions
- meniscal injury and cartilage loosening.
- Registration Number
- NL-OMON26079
- Lead Sponsor
- Investigator initiated study
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
focal cartilage lesions, ICRS grade 2-3a (i.e. partial thickness) (Brittberg and Peterson, 1998)
- age =18y
Exclusion Criteria
- subjects with general contraindications for MRI scanning
- a known allergic reaction to gadolinium-containing contrast agents
- renal insufficiency (glomerular filtration rate, <60 mL/min)
- Subjects who do not understand Dutch written language, necessary for completing the PROMS
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is the dGEMRIC index (T1gd, in ms) at one year follow-up of the treated region
- Secondary Outcome Measures
Name Time Method - T1gd (ms) at healthy regions surrounding the treated area will be measured for reference<br>- Patient reported outcome of knee function, quality of life and pain will be collected preoperatively, and at 3, 6 and 12 months