Effects of osteotomies around the knee on cartilage glycosaminoglycan content using dGEMRIC non-invasive imaging
Completed
- Conditions
- joint degenerationosteoarthritis10023213
- Registration Number
- NL-OMON31458
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
Osteoarthritis of the knee
Planned osteotomy above or below the knee
Exclusion Criteria
Contra-indications for MRI scanning, using Gadolinium as a contrast agent
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The measurement of the average T1-value will be performed measuring the<br /><br>distance from the location with the worst T1-signal to the center axis of the<br /><br>upper and lower limb. Further, changes in intensity of T1 signal will be<br /><br>measured to evaluate progression or decrease of cartilage damage. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Above mentioned outcomes will be correlated to questionnaires, measuring<br /><br>clinical effectiveness of the procedure (KOOS, VAS, Knee Society Scale).</p><br>