Utilizing MRI for Earlier Diagnosis of Rheumatoid Arthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Earlier Diagnosis of RA if MRI is utilized
研究概览
简要总结
MRI has been shown to be helpful in identifying patients who present with undifferentiated inflammatory arthritis who will develop RA within a one year follow up period. The absence of other clinically apparent symptoms often causes delays in diagnosis of RA. The use of the MRI in conjunction with the physical examination has the potential to reduce diagnostic delay. Earlier diagnosis would allow for earlier treatment implementation for better patient outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 18 years old
- •Undifferentiated inflammatory arthritis suspected to be early RA (≥1 joint with synovitis and ≥1 other tender joint)
- •Symptom duration ≤1 year
排除标准
- •Unwillingness or inability to return to Mayo Clinic Rochester for research follow-up visits
- •Current or previous use of DMARDS
- •Taking ≥10 mg of prednisone a day
- •Contraindications to contract enhanced MRI
- •History of another definite autoimmune or inflammatory rheumatic disease
- •History of psoriasis
- •History of inflammatory bowel disease
- •Unsuitably as deemed by the principal investigator
结局指标
主要结局
Earlier Diagnosis of RA if MRI is utilized
时间窗: 1 year
To determine if MRI is predictive of later development of RA in patients with undifferentiated inflammatory arthritis; patients with inflammatory arthritis who receive an MRI will have earlier initiation of treatment
次要结局
未报告次要终点
