ACTRN12614000895684
Active, not recruiting
未知
MRI inflammation as an imaging biomarker in rheumatoid arthritis: comparing the change in MRI-inflammation scores between patients receiving treatment for disease flare with combination conventional disease suppressing therapy and those commencing combination methotrexate/anti-tumour necrosis factor (TNF) therapy
Prof Fiona McQueen0 sites100 target enrollmentAugust 22, 2014
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- rheumatoid arthritis
- Sponsor
- Prof Fiona McQueen
- Enrollment
- 100
- Status
- Active, not recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •seropositive rheumatoid arthritis
- •Willing and eligible for disease modifying therapy including methotrexate, combination DAMRDS and /or anti\-TNF therapy as per treating clinician's decision
- •Willing and eligible to have 2 contrast\-enhanced MRI scans (no contraindications)
Exclusion Criteria
- •Contraindications to the medical therapies for rheumatoid arthritis as outlined above
- •Patients will be excluded if there are contraindications to MRI scanning (obesity, claustrophobia, internal metalware) or have impaired renal function and cannot be given IV gadolinium (creatinine clearance must be \> 60ml/min).
Outcomes
Primary Outcomes
Not specified
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