RESCUE PROTOCOL AND FRESH EMBRYO TRANSFER
- Registration Number
- NCT03837223
- Lead Sponsor
- Istituto Clinico Humanitas
- Brief Summary
Ovarian Hyperstimulation Syndrome (OHSS) is one of the most dangerous complications of Assisted Reproductive Technologies (ART) cycles. The use in clinical practice of the GnRH antagonist has made it possible to perform the trigger with GnRH analogues reducing the risk of OHSS. The trigger with analogue increases the Abortion Rate (AR) and reduces the Ongoing Pregnancy Rate (OPR), because the luteal phase in these cycles is particularly deficient. To reduce this occurrence several studies have focused on the importance of support of the luteal phase. The aims of study is to evaluate OPR and AR in patients at intermediate risk of OHSS (\<18 recovered oocytes) which performed GnRH trigger and rescue protocol.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 271
AMH ( antimullerian hormone) > 3.5 ng / ml, AFC (antral follicles count) > 15 follicles and if more than 18 follicles with diam. 12mm to induction
high risk of OHSS ( ovarian hyperstimulation syndrome)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description patients underwent "rescue protocols" and fresh embryotransfer GnRH agonist they were patients with good prognosis with a mean age of 34.13 ± 4.42 years, with a good ovarian reserve
- Primary Outcome Measures
Name Time Method ongoing pregnancy rate (OPR) 2013-2018 presence of gestational sac and fetal hearts beats showed on unltrasonography 7/8 weeks after embryo transfer
- Secondary Outcome Measures
Name Time Method