Osteoarticular Infections With Pneumococcal

Completed

• Conditions: Bone and Joint Infection
• Interventions: Other: Bone and joint infection with Streptococcus peumoniae

• Registration Number: NCT03852784
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Osteoarticular infections at pneumococcal are rare, potentially serious and remain under diagnosed. They represent 3 at 10% of the arthritis septic in the literature. 190 cases have been published of 1965 at 2003. They represent 0.3% at 0.6% of the bacteraemia at Streptococcus peumoniae.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-01
• Study First Submitted: 2019-02-21
• Study First Submitted QC: 2019-02-21
• Study First Posted: 2019-02-25
• Primary Completion: 2019-03-01
• Study Completion: 2020-04-01
• Status Verified: 2023-09
• Last Update Submitted: 2023-09-21
• Last Update Posted: 2023-09-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

• patients having had a bone and joint infection with S pneumoniae, with or without device.

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Exclusion Criteria

• none

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Bone and joint infection with Streptococcus peumoniae	Bone and joint infection with Streptococcus peumoniae	Patients having had an osteoarticular infection with Streptococcus peumoniae

Primary Outcome Measures

Name	Time	Method
Description and rate of bone or joint infection with S. pneumoniae	Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption	Description of the type of infection due to S. pneumoniae : patients and type of implant, profile of the bacterium associated in the infection, medical and chirurgical treatment

Secondary Outcome Measures

Name	Time	Method
Rate of Treatment Failure	Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption	Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin

Trial Locations

Locations (1)

Hospices Civils de Lyon; 🇫🇷 Lyon, France