Spectrum of Bacterial Infections in Rheumatology
- Conditions
- Articular Disease
- Registration Number
- NCT05007405
- Lead Sponsor
- Hôpital NOVO
- Brief Summary
Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are :
* To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome
* To compare OAI of urinary origin with those with another origin
- Detailed Description
This retrospective study will be conducted on medical files. Patients will be mainly selected on :
* A proved osteoarticular infection (OAI) diagnosed in the department of rheumatology of the René Dubos hospital from 1° January 2010 to 31 December 2020.
* Adult patients 18 year's old or older
* Infection proved by positive culture in the osteoarticular site and/or blood (with typical clinical and imaging features)
The followed OAI are not included :
* Infection on prosthetic joint, materiel ; post-operative OAI ; osteomyelitis
* Brucellosis ; Lyme disease
Patients are selected from the codification of the hospitalization ; medical files are reviewed by the investigators.
OAI of urinary origin is defined either by the same micro-organism in urine and osteo-articular sample (or blood) or a bacteria in the osteo-articular sample in conjunction with : urologic pathology, recurrent urinary tract infection, urologic surgery, antibiotic therapy.
* Characteristics of three populations will be compared :
* - OAI of urinary origin
* - OAI of another origin (skin, etc)
* - OAI without known origin Characteristics include : gender, age, risk factors, site of osteo-articular infection, type of micro-organism, type of positive sample(s), blood cultures, urinary cultures, duration of symptoms, site of primary infection and/or type of contamination, biological results, echocardiography, imaging results, type of treatment (medical, surgical), outcome, duration of hospitalization, intensive unit care stay, death at hospital.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 81
- Subject aged 18 years and over at the time of diagnosis
- Osteoarticular infection (septic arthritis, spondylodiscitis), by a bacterium or a fungus, proven by a bacteriological sample in situ or in the blood by positive blood culture (with an unequivocal clinical, biological and imaging feature),
- Diagnosed between 01/01/2010 and 12/31/2020 (11 years)
- Hospitalization in the rheumatology department of CH René Dubos, Pontoise
- Bacterial infection due to the following germs: mycobacteria, brucella, Borrelia
- Early infection on joint prosthesis
- Peripheral osteomyelitis
- Osteoarticular infection without bacteriological proof
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identification of the spectrum of osteoarticular infections in adult, in a rheumatology department Through study completion, an average of 1 year The purpose of this database is to describe the spectrum of osteoarticular infections in adults, non-tuberculosis germs, in a rheumatology department of a CHG during the 2010s
- Secondary Outcome Measures
Name Time Method Prevalence of urinary origin in osteoarticular infections in adults, compared with other origins Through study completion, an average of 1 year The second purpose of this database is to identify the characteristics of osteo-articular infections of urinary origin
Trial Locations
- Locations (1)
Department of Rheumatology, Hospital René Dubos, Pontoise
🇫🇷Pontoise, France
Department of Rheumatology, Hospital René Dubos, Pontoise🇫🇷Pontoise, France