Alterations of the gut microbiome in patients with IBS in correlation to illness anxiety and symptom severity

• Conditions: K58; F45.32; Irritable bowel syndrome

• Registration Number: DRKS00033141
• Lead Sponsor: niversitätsklinikum Heidelberg, Abteilung für Allgemeine Innere Medizin und Psychosomatik

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-18
• Study Completion: 2024-01-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Irritable Bowel Syndrome in the clinical assessment
Irritable Bowel Syndrome according to the Rome-IV-Criteria
Signed informed consent

Exclusion Criteria

Chronic inflammatory bowel disease
Severe psychopathologies such as acute suicidality or current substance dependence
Recent use of antibiotics within the past two weeks

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Description of patients with irritable bowel syndrome

Secondary Outcome Measures

Name	Time	Method
Interactions between the composition of the gut microbiome and the severity of IBS symptoms (IBS-SSS), illness anxiety (WI-7) and further psychosocial factors.