„Changes in the gastrointestinal microbiome after kidney transplantatio
- Conditions
- Z94.0Kidney transplant status
- Registration Number
- DRKS00011015
- Lead Sponsor
- Klinik für AnästhesiologieUniversitätsklinikum Heidelberg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Consent of agreement of participant
-patients undergoing a kidney transplantation (Graft from a living donor)
Exclusion Criteria
missing satisfaction of inclusion criteria, pregnancy, HIV positive, denial of participation
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Following points are being researched as a main criteria in patients after kidney transplantation performed at a german university medical center:<br><br>Sequencing of donor’s as well as graft receiving patient’s gastrointestinal microbiome via 16s RNA analysis.<br><br>To work out changes in receiving patient’s microbiome via 16S RNA analysis as a consequence of immunosuppressive therapy.<br><br> Stool samples will be collected at following days: Before surgery (during consultation hour); T1 (first day after surgery); T3 (third day after surgery); <br>T5 (fifth day after surgery); T10 (tenth day after surgery).<br>
- Secondary Outcome Measures
Name Time Method evaluation of possible connection between gastrointestinal microbiome and individual outcome