Bereavement in Children, Adolescents and Young Adults. - A Study of Health and Psychosocial Well-being in Adults Who Have Experienced Early Parental Death
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,225,660
- 试验地点
- 1
- 主要终点
- Severe cardiovascular disease
研究概览
简要总结
The purpose of this study is to examine how the death of a parent as a child, adolescent or young adult affects health and psychosocial wellbeing in adult life and to evaluate the impact in adult life of counseling to children, adolescents and young adults who lost a parent.
详细描述
Early parental death experienced by 4% of the children in Western countries, is considered to be the most stressful and potentially harmful childhood life event and the health consequences may depend on the nature of the bereavement (e.g. relationship with bereaved), as well as by interpersonal (e.g. social support), intrapersonal (e.g. age and genetics), appraisal and coping factors. Studies have shown that children and adolescents have a greater risk of getting a psychiatric diagnose as well as psychological and social problems. Despite of the obvious consequences of losing a parent, there is a lack of systematic studies on the consequences later in life as well as studies that evaluate the counseling possibilities the children and adolescents are offered.
The study will investigate:
- Long-term health effects of experiencing parental death as a child adolescent or young adult. Focus will be on psychiatric outcomes including depression, severe cardiovascular disease, suicide, suicide attempts, psychological well-being and health related behavior.
- Long term effects of experiencing parental death as a child, adolescent or young adult on socioeconomic outcomes as education, employment, marital status/ cohabitation status and number of children/age when having children.
- The long-term psychosocial and behavioral impact of psychological intervention programmes to children, adolescents and young adults who have experienced the death of a parent. Focus will be on: Depressive symptoms, quality of life, posttraumatic stress disorder, life style, relationship functioning, grief and spirituality.
A nationwide register based cohort of people born in Denmark will be established. Long-term health effects and socioeconomic outcomes of experiencing parental death will be based on nationwide clinical and administrative registries. Exposure is defined as experiencing the death of a parent before age 30. The long-term psychosocial and behavioral impact of psychological intervention programmes will be based on a combination of questionnaire data and data from registries.
The part of the study using data from registries will be based on the nationwide cohort. The questionnaire based part of the study will include 3 groups selected from the nationwide cohort:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •persons born in Denmark
排除标准
- 未提供
结局指标
主要结局
Severe cardiovascular disease
时间窗: Paticipants will be followed from age 18 until date of first hospitalization for severe cardiovascular disease, death, first emigration or end of follow up, an expected average of 15 years
The Danish National Patient Register
Quality of life
时间窗: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)
SF-36, Self-reported questionnaire
Hospitalization for affective disorder
时间窗: Paticipants will be followed from age 15 until date of first hospitalization for an affective disorder, death, first emigration or end of follow up, an expected average of 12 years
Danish Psychiatric Central Register
Use of antidepressive medication
时间窗: Paticipants will be followed from age 20 until date of second independantly prescription of antidepressive medication, death, first emigration or end of follow up, an expected average of 9 years
The Danish National Prescription Registry
Employment
时间窗: Employment status at age 30, death, first emigration or end of follow-up, an expected average of 8 years.
The Register-based System of Demographics and Social Statistics in Denmark
Complicated grief
时间窗: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)
Inventory of Complicated Grief/ Prolonged Grief Disorder (PG-13) and Centrality of Event Scale, Self-reported questionnaire
PTSD
时间窗: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)
Harvard Trauma Questionnaire (HTQ), Self-reported questionnaire
Depressive symptoms
时间窗: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)
The Center for Epidemiological Studies Depression Scale (CES-C)
Suicide
时间窗: Paticipants will be followed from age 18 until date of suicide, other causes of death, first emigration or end of follow up, an expected average of 15 years
Danish Register of Causes of Death
Existentiality
时间窗: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)
Posttraumatic Growth Inventory (PTGI, Self-reported questionnaire
Education level
时间窗: Participants will be followed from age 18 until highest attained educational level, death, first emigration or end of follow up, an average of 20 years
The Register-based System of Demographics and Social Statistics in Denmark
次要结局
- Relationship functioning(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))
- Support when losing a parent(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))
- Lifestyle (smoking, alcohol, exercise)(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))
- Coping(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))
研究者
Christoffer Johansen
Head of Department of Psychosocial Cancer Research
Danish Cancer Society