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Clinical Trials/NCT01453699
NCT01453699
Completed
Not Applicable

Bereavement in Children, Adolescents and Young Adults. - A Study of Health and Psychosocial Well-being in Adults Who Have Experienced Early Parental Death

Danish Cancer Society1 site in 1 country1,225,660 target enrollmentSeptember 2009
ConditionsBereavement

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bereavement
Sponsor
Danish Cancer Society
Enrollment
1225660
Locations
1
Primary Endpoint
Severe cardiovascular disease
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

The purpose of this study is to examine how the death of a parent as a child, adolescent or young adult affects health and psychosocial wellbeing in adult life and to evaluate the impact in adult life of counseling to children, adolescents and young adults who lost a parent.

Detailed Description

Early parental death experienced by 4% of the children in Western countries, is considered to be the most stressful and potentially harmful childhood life event and the health consequences may depend on the nature of the bereavement (e.g. relationship with bereaved), as well as by interpersonal (e.g. social support), intrapersonal (e.g. age and genetics), appraisal and coping factors. Studies have shown that children and adolescents have a greater risk of getting a psychiatric diagnose as well as psychological and social problems. Despite of the obvious consequences of losing a parent, there is a lack of systematic studies on the consequences later in life as well as studies that evaluate the counseling possibilities the children and adolescents are offered. The study will investigate: 1. Long-term health effects of experiencing parental death as a child adolescent or young adult. Focus will be on psychiatric outcomes including depression, severe cardiovascular disease, suicide, suicide attempts, psychological well-being and health related behavior. 2. Long term effects of experiencing parental death as a child, adolescent or young adult on socioeconomic outcomes as education, employment, marital status/ cohabitation status and number of children/age when having children. 3. The long-term psychosocial and behavioral impact of psychological intervention programmes to children, adolescents and young adults who have experienced the death of a parent. Focus will be on: Depressive symptoms, quality of life, posttraumatic stress disorder, life style, relationship functioning, grief and spirituality. A nationwide register based cohort of people born in Denmark will be established. Long-term health effects and socioeconomic outcomes of experiencing parental death will be based on nationwide clinical and administrative registries. Exposure is defined as experiencing the death of a parent before age 30. The long-term psychosocial and behavioral impact of psychological intervention programmes will be based on a combination of questionnaire data and data from registries. The part of the study using data from registries will be based on the nationwide cohort. The questionnaire based part of the study will include 3 groups selected from the nationwide cohort: 1. Persons who have lost a parent and participated in intervention programmes (identified through counseling centers), 2. Persons who have lost a parent, and not participated in intervention programmes (randomly selected matched on age and gender) and 3. Persons who have not lost a parent (randomly selected matched on age and gender). An invitation letter will be send to the 3 groups (5500 persons) by mail, and they will be asked to complete one questionnaire online.

Registry
clinicaltrials.gov
Start Date
September 2009
End Date
November 2012
Last Updated
11 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Christoffer Johansen

Head of Department of Psychosocial Cancer Research

Danish Cancer Society

Eligibility Criteria

Inclusion Criteria

  • persons born in Denmark

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Severe cardiovascular disease

Time Frame: Paticipants will be followed from age 18 until date of first hospitalization for severe cardiovascular disease, death, first emigration or end of follow up, an expected average of 15 years

The Danish National Patient Register

Quality of life

Time Frame: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

SF-36, Self-reported questionnaire

Hospitalization for affective disorder

Time Frame: Paticipants will be followed from age 15 until date of first hospitalization for an affective disorder, death, first emigration or end of follow up, an expected average of 12 years

Danish Psychiatric Central Register

Use of antidepressive medication

Time Frame: Paticipants will be followed from age 20 until date of second independantly prescription of antidepressive medication, death, first emigration or end of follow up, an expected average of 9 years

The Danish National Prescription Registry

Employment

Time Frame: Employment status at age 30, death, first emigration or end of follow-up, an expected average of 8 years.

The Register-based System of Demographics and Social Statistics in Denmark

Complicated grief

Time Frame: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Inventory of Complicated Grief/ Prolonged Grief Disorder (PG-13) and Centrality of Event Scale, Self-reported questionnaire

PTSD

Time Frame: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Harvard Trauma Questionnaire (HTQ), Self-reported questionnaire

Depressive symptoms

Time Frame: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

The Center for Epidemiological Studies Depression Scale (CES-C)

Suicide

Time Frame: Paticipants will be followed from age 18 until date of suicide, other causes of death, first emigration or end of follow up, an expected average of 15 years

Danish Register of Causes of Death

Existentiality

Time Frame: Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Posttraumatic Growth Inventory (PTGI, Self-reported questionnaire

Education level

Time Frame: Participants will be followed from age 18 until highest attained educational level, death, first emigration or end of follow up, an average of 20 years

The Register-based System of Demographics and Social Statistics in Denmark

Secondary Outcomes

  • Relationship functioning(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))
  • Support when losing a parent(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))
  • Lifestyle (smoking, alcohol, exercise)(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))
  • Coping(Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years))

Study Sites (1)

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