Dynamic first pass CT perfusion imaging of the myocardium vs. intracoronary transluminal attenuation gradient in coronary CT angiography for the assessment of coronary artery stenosis

• Conditions: I24; I25; Other acute ischaemic heart diseases; Chronic ischaemic heart disease

• Registration Number: DRKS00014579
• Lead Sponsor: Institut für diagnostische und interventionelle Radiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2012-05-18
• Study Start: 2018-04-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

clinical indication to perform a coronary CT angiography

Exclusion Criteria

Atrial fibrillation, the inability to perform a 30-s-breathhold, acute coronary syndrome within 14 days of either procedure, high-degree atrioventricular block, hypotension with a systolic blood pressure < 90 mm Hg, severe chronic obstructive pulmonary disease or decompensated congestive heart failure (NYHA Classification III or IV), history of allergy to iodinated contrast material, history of active hyperthyroidism among patients older than 60 years of age, serum creatinine levels greater than 1.5 mg/dL (132.6 µmol/L) and pregnancy or breastfeeding

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of the diagnostic accuracy of CT perfusion imaging in comparison to the gold standard of invasive coronary angiography with invasive pressure wire examination; patients underwent all examinations within 2 weeks

Secondary Outcome Measures

Name	Time	Method
Evaluation of the diagnostic accuracy of CT Perfusion Imaging compared to the diagnostic accuracy of Transluminal attenuation Gradient ; patients underwent all examinations within 2 weeks