Detection of myocardial ischemia by CT perfusion imaging in comparison with N-13 ammonia PET
- Conditions
- coronary artery disease
- Registration Number
- JPRN-UMIN000015856
- Lead Sponsor
- Tokyo Women's Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Not provided
1. Body weight >75kg 2. Elevated serum creatinine (>1.5 mg/dL) or calculated creatinine clearance of <60 mL/min 3. History of allergic reaction to iodinated contrast media, History of contrast-induced nephropathy 4. Atrial fibrillation or uncontrolled tachyarrhythmia 5. Advanced atrioventricular block (second- or third-degree heart block) 6. Evidence of acute coronary syndrome 7. Known or suspected moderate or severe aortic stenosis 8. Evidence of severe symptomatic heart failure (New York Heart Association class III or IV) 9. Previous coronary artery bypass or other cardiac surgery 10. Coronary artery intervention within the past 6 months 11. Contraindications to vasodilatory stress (systolic blood pressure <90, recent use of dipyridamole- and dipyridamole-containing medications, recent use of methylxanthines, such as aminophylline and caffeine) 12. Profound sinus bradycardia (fewer than 40 beats per minute) 13. Known or suspected intolerance or contraindication to beta-blockers (including known allergy to betablockers, history of moderate to severe bronchospastic lung disease, including moderate to severe asthma, severe pulmonary disease with the use of inhaled bronchodilator over the past year) 14. Presence of intracardiac devices, such as intracardiac defibrillator or metallic implants within the imaging field of view 15. History of high radiation exposure (>2 nuclear or multidetector CT studies) in the 1 month before consent 16. The presence of any other history or condition that the investigator judged to be a significant reason for exclusion
Study & Design
- Study Type
- Interventional,observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diagnostic accuracy of combination of CT perfusion and CT coronary angiography for detecting myocardial ischemia
- Secondary Outcome Measures
Name Time Method