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临床试验/NCT03689101
NCT03689101已完成不适用

To Explore the Relationship Between Endometrial CD138 Count and Pregnancy Outcome Following Frozen Embryo Transfer in Natural Cycles

Reproductive & Genetic Hospital of CITIC-Xiangya1 个研究点 分布在 1 个国家目标入组 148 人开始时间: 2016年3月21日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
148
试验地点
1
主要终点
CD138 counting

研究概览

简要总结

It's well known, endometritis affects reproductive outcomes. Though CD138 counting as one new diagnosis measure for endometritis, diagnostic criterion of this measure isn't consistent. And if the CD138 counting is correlation to the outcome of reproductive is not clear.

Firstly, This study aims to explore the relationship between endometrial CD138 count and pregnancy outcome following frozen embryo transfer in natural cycles. Secondly , the investigators want to find a cut-off value which is related to reproduction outcome.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
20 Years 至 38 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • age between20 and 38 years;
  • regular menstrual cycles;
  • body mass index (BMI) ranged from 18 to 25

排除标准

  • uterine abnormalities;
  • intrauterine adhesions(moderate - severe), advanced endometriosis, adenomyosis, untreated hydrosalpinx, uterine fibroids (submucosal fibroids, nonmucosal fibroids >4.0 cm and/or endometrial pressure)

结局指标

主要结局

CD138 counting

时间窗: 7 days after LH surge (LH+7)

clinical pregnancy rate

时间窗: about 28 days after embryo transfer

次要结局

未报告次要终点

研究者

发起方
Reproductive & Genetic Hospital of CITIC-Xiangya
申办方类型
Other
责任方
Sponsor

研究点 (1)

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