Chronic Heart Failure - Cheyne Stokes Respiration - CS2 (3C-study)
Not Applicable
Completed
- Conditions
- Heart FailureCheyne Stokes Respiration
- Interventions
- Device: ASVOther: without Autoset CS2
- Registration Number
- NCT00563693
- Lead Sponsor
- University of Oslo
- Brief Summary
An investigation where patients with chronic heart failure and cheyne stokes respiration, treated with adapitve servo ventilator, will improve their cardiac function and quality of life.
- Detailed Description
Chronic heart failure (HF) is one of the most important public health problems in cardiovascular medicine.
Several patients with chronic heart failure also has Cheyne Stokes respiration pattern. Earlier studies have shown that this respiration pattern improves with Adaptive servo ventilator. We wish to investigate wether this leads to improved cardiac function.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Ejection fraction <40%
- NYHA class III-IV
- Optimized therapy with drugs
- Cheyne stokes respiration pattern > 25% while sleeping
- Age < 85 years
- clinical stability the last month before inclusion.
Exclusion Criteria
- CABG less then 6 months ago
- PCI treatment less then 3 months ago
- Unstable angina pectoris
- Acute coronary syndrome less then 3 months ago
- Stroke less then 6 weeks ago
- Thoracal myopathy
- Advanced COPD
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description A ASV The patients use ASV B without Autoset CS2 Patients without ASV A without Autoset CS2 The patients use ASV
- Primary Outcome Measures
Name Time Method Ejection fraction (measured with echocardiography) and inflammatory markers 3 months
- Secondary Outcome Measures
Name Time Method 6 minutes walking test Quality of life Changes in cathecolamines Altered frequency of arrythmias 3 months
Trial Locations
- Locations (1)
Sykehuset ostfold Fredrikstad
🇳🇴Fredrikstad, Norway