Diagnostic Value of HS-CRP in Stable Angina.

Not Applicable

Completed

• Conditions: Stable Angina; Positive ETT
• Interventions: Procedure: coronary angiography

• Registration Number: NCT00719992
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

The aim of this study was to assess the amount of additive value of HS-CRP levels to a positive exercise tolerance test (ETT) in predicting coronary artery disease (CAD) using coronary angiography as the gold standard. The investigators concluded that HS-CRP can be used as a single predictor of coronary vessel involvement in patients with stable angina and positive ETT.

Detailed Description

the investigators included 97 patients with positive ETT and stable angina and saw that Hs-CRP is the only predictor of severity of CAD as compared with coronary angiography in stable angina patients.

Study Timeline

• Study Start: 2006-04
• Primary Completion: 2007-08
• Study Completion: 2007-08
• Status Verified: 2008-07
• Study First Submitted: 2008-07-18
• Study First Submitted QC: 2008-07-18
• Last Update Submitted: 2008-07-18
• Study First Posted: 2008-07-22
• Last Update Posted: 2008-07-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 97

Inclusion Criteria

• Stable angina
• Positive ETT

Exclusion Criteria

• Unability to perform ETT
• Contraindications for ETT and angiography study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	coronary angiography	positive ETT, High HS-CRP
2	coronary angiography	positive ETT, Low HS-CRP

Primary Outcome Measures

Name	Time	Method
significant coronary lesion

Secondary Outcome Measures

Name	Time	Method
severity of CAD

Trial Locations

Locations (1)

Cardiology Ward Shiraz University of Medical Sciences; 🇮🇷 Shiraz, Fars, Iran, Islamic Republic of