Comparison Between Spinal and General Anesthesia in Neonates Undergoing Herniorrhaphy: A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Spinal Anesthesia
- Sponsor
- Tanta University
- Enrollment
- 74
- Locations
- 1
- Primary Endpoint
- Heart rate
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of this study is to compare spinal and general anesthesia in neonates undergoing herniorrhaphy.
Detailed Description
Spinal anesthesia (SA) is a fast, simple and cost-effective method that has been used for the performance of inguinal hernias since the beginning of the 20th century in adults. One large observational study documented a low risk of post operative events with spinal anesthesia for inguinal hernia repair in infants . In addition, a randomized trial comparing reginal and general anesthesia in this population have not shown any significant differences in outcome. Spinal anesthesia reduces postoperative oxygen desaturation and respiratory morbidity when compared to general anesthesia (GA) in infants who underwent inguinal herniorrhaphy
Investigators
Mohammed Said ElSharkawy
Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University
Eligibility Criteria
Inclusion Criteria
- •Neonates either full term or preterm.
- •Both sexes.
- •American Society of Anesthesiologists (ASA) physical status I-II
- •Undergoing unilateral or bilateral inguinal herniorrhaphy.
Exclusion Criteria
- •Obstructed hernia.
- •Neonates with significant chronic lung disease (e.g., disease associated with hypoxemia in room air or chronic hypercapnia).
- •Symptomatic congenital heart disease (e.g., cyanosis or congestive heart failure).
- •Symptomatic central nervous system disease (e.g., seizures).
Outcomes
Primary Outcomes
Heart rate
Time Frame: Immediately postoperatively at post-anesthesia care unit
Heart rate will be recorded at post-anesthesia care unit.
Secondary Outcomes
- Heart rate(Till two hours postoperatively)
- The duration of surgery(Till the end of surgery)
- Incidence of hypotension(24 hours postoperative)
- Mean arterial blood pressure(Till two hours postoperatively)
- Incidence of bradycardia(24 hours postoperative)
- Incidence of postoperative apnea(24 hour postoperatively)
- Need for postoperative O2 supplementation(Till two hours postoperatively)
- Hospital stays(28 days postoperative)