Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task

Not Applicable

• Conditions: Electromyography; Fatigue; Alkalosis, Metabolic; Sodium Bicarbonate
• Interventions: Dietary Supplement: Sodium bicarbonate; Dietary Supplement: Calcium carbonate

• Registration Number: NCT03837886
• Lead Sponsor: University of Nove de Julho

Brief Summary

The aim of this study was to verify if sodium bicarbonate (NaHCO3) suplementation promotes changes in the performance, muscular activity and strength of individuals trained during the intermittent and intense task . Twelve trained adult men will participate in this randomized, double-blind, crossover clinical trial. Each participant should receive two types of intervention with a 14-day interval between conditions: alkalosis (ALK) in which gelatinous capsules containing 0.3 g.kg -1 of NaHCO 3 and placebo (PLA) are administered, in which 0.3 g.kg-1 of Calcium Carbonate (CaCO3). The following results will be considered: electromyographic activity (EMG) of the quadriceps muscle, peak torque, pH, lactate, and perception of effort, recovery and pain questionnaires, which will be collected during intermittent and high intensity DI protocol. ANOVA of repeated measures will be used to verify possible differences between groups.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-02-06
• Study First Submitted QC: 2019-02-08
• Study First Posted: 2019-02-12
• Status Verified: 2019-10
• Last Update Submitted: 2019-10-16
• Last Update Posted: 2019-10-17
• Study Start: 2019-10-20
• Primary Completion: 2019-10-30
• Study Completion: 2019-11-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• resistance trained men (minimum 12 moths resistance training experience)

Exclusion Criteria

• diabetes mellitus;
• respiratory (asthma, COPD), renal, metabolic, rheumatic and cardiovascular disorders;
• acid-base balance disorder;
• continuous use of some type of medication;
• use of high-protein supplementation and creatine supplementation;
• users of anabolic steroids.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Alkalosis group	Sodium bicarbonate	The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of sodium bicarbonate
Placebo group	Calcium carbonate	The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate

Primary Outcome Measures

Name	Time	Method
Electromyographic activity of the femoral quadriceps evaluated with electromyography equipment	60 minutes	The electromyographic activity will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets in an isokinetic dynamometer.
Peak torque assessed with isokinetic dynamometer equipment	60 minutes	The peak torque will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets.

Secondary Outcome Measures

Name	Time	Method
Lactate assessed with portable lactometer	15 seconds	The lactate quantification will be performed before and after the test session characterized by the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with an interval of 1 minute between sets in an isokinetic dynamometer.

Trial Locations

Locations (1)

Nove de Julho University; 🇧🇷 São Paulo, Brazil