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Sodium Bicarbonate Supplementation in Combat Sports Athletes

Phase 2
Completed
Conditions
Sport
Supplementation
Interventions
Dietary Supplement: Placebo treatment
Dietary Supplement: Sodium bicarbonate supplementation
Registration Number
NCT03406065
Lead Sponsor
Poznan University of Life Sciences
Brief Summary

The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on physical and specific performance capacity, as well as concentrations of the selected biochemical blood markers in trained combat sports athletes, in a randomised, double-blind, placebo-controlled trial.

Detailed Description

Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive-dose NaHCO3 ingestion on physical capacity and specific performance capacity, and concentrations of the selected biochemical blood markers in trained combat sports athletes, in a randomised, double-blind, placebo-controlled trial.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
64
Inclusion Criteria
  • written informed consent from all participants before the study (included aslo informed consents to the participation in the study of athletes under the age of 18 obtained from their parents)
  • a current medical clearance to practice sports,
  • training experience: at least 4 years (of combat sport training),
  • minimum of 4 workout sessions (combat sport) a week,
Exclusion Criteria
  • current injury,
  • any health-related contraindication,
  • declared general feeling of being unwell,
  • unwilling to follow the study protocol.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Placebo treatmentPlacebo treatmentGroup taking oral supplementation with placebo (maltodextrin with NaCl) in a similar tablet form prepared by the same producer as NaHCO3 tablets.
Sodium bicarbonate supplementationSodium bicarbonate supplementationGroup taking oral NaHCO3 supplementation in a progressive-dose regimen.
Primary Outcome Measures
NameTimeMethod
Changes in anaerobic capacity after sodium bicarbonate supplementationBaseline and after 10 days

The Wingate Anaerobic Test (WAnT)

Changes in specific performance capacity after sodium bicarbonate supplementationBaseline and after 10 days

The wrestler's special endurance test - projective test with dummy (DT)

Secondary Outcome Measures
NameTimeMethod
Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementationBaseline and after 10 days

Hemoglobin (Hb) \[g/dl\] and glucose \[g/dl\] concentration analysis

Changes in blood hematocrit levels after sodium bicarbonate supplementationBaseline and after 10 days

Hematocrit (HCT) \[%\] level analysis

Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementationBaseline and after 10 days

Red blood cells (RBC) \[mln/mm³\] and white blood cells (WBC) \[mln/mm³\] concentration analysis

Changes in FRAP concentrationBaseline and after 10 days

FRAP \[µmol/L\] concentration analysis

Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementationBaseline and after 10 days

Creatine kinase \[U/L\] and lactate dehydrogenase \[U/L\] activity analysis

Changes in polyphenols and albumin concentrationBaseline and after 10 days

Polyphenols \[g/L\] and and albumin \[g/L\] concentration analysis

Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementationBaseline and after 10 days

Lactate \[mmol/L\] and pyruvate \[mmol/L\] concentration analysis

Trial Locations

Locations (1)

Poznan University of Life Sciences, ul.Wojska Polskiego 31

🇵🇱

Poznań, Wielkopolska, Poland

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