Assessment of the Accuracy of PET/MR in Detection and Monitoring Response of Bone Metastases

Not Applicable

• Conditions: Bone Metastases

• Registration Number: NCT04159376
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

The great promise of PET/MR for assessment of skeletal metastatic involvement is derived from the extensive experience with stand- alone MR, but initial data on the use of PET/MR for assessment of bone pathology indicate that PET/MR introduces unique issues that should be addressed when determining its role in this clinical scenario.

In this study cohort includes 150 patients 18 years or older, having metastatic skeletal involvement on baseline PET/CT prior to treatment. Baseline studies and follow up studies of the patients referred post treatment, will be reviewed.

The main goal of the study is to asses the accuracy of PET/MR in detection and monitoring response of bone metastases.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-10-29
• Status Verified: 2019-11
• Study First Submitted QC: 2019-11-07
• Last Update Submitted: 2019-11-07
• Study First Posted: 2019-11-12
• Last Update Posted: 2019-11-12
• Study Start: 2019-12-25
• Primary Completion: 2020-02-25
• Study Completion: 2021-12-25

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

150 patients having metastatic skeletal involvement on baseline PET/CT prior to treatment

Exclusion Criteria

1. Age <18.
2. Pregnant or breast feeding patients.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
The investigators will report about the number of patients who preformed PET/MR for assessment of skeletal involvement as well as activity after treatment,	1 year	and also preformed in routine PET/CT and to optimize the algorithm of MR-based attenuated PET images.