Assessing Renal Function in Patients With an Antibiotic Laden Spacer

• Conditions: Infected Total Hip or Knee Arthroplasty

• Registration Number: NCT01683734
• Lead Sponsor: Central DuPage Hospital

Brief Summary

The purpose of this study is to monitor the renal function of patients who have an antibiotic laden spacer in place to treat an infected hip or knee arthroplasty.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05
• Study First Submitted: 2012-08-28
• Study First Submitted QC: 2012-09-10
• Study First Posted: 2012-09-12
• Status Verified: 2015-02
• Last Update Submitted: 2015-02-03
• Last Update Posted: 2015-02-04
• Primary Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. All patients undergoing a hip or knee resection arthroplasty by the primary investigator
2. Ages 18+
3. Ability to adhere to follow up schedule

Exclusion Criteria

1. Unable to give informed consent
2. Age <18
3. Previous history of infected Total Knee Arthroplasty or Total Hip Arthroplasty
4. History of renal failure or impaired renal function
5. Allergies to aminoglycosides or Vancomycin

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Development of acute renal insufficiency or acute renal failure measured by changes in laboratory values assessing renal function	subjects will be followed during the time the antibiotic spacer is in place which is approximately 8 weeks

Trial Locations

Locations (2)

RUSH University Medical Center; 🇺🇸 Chicago, Illinois, United States

Central DuPage Hospital; 🇺🇸 Winfield, Illinois, United States