How effective kulatthadi Kashay is will be checked in dysmenorrhea patients

Phase 2/3

Not yet recruiting

Conditions: Primary dysmenorrhea. Ayurveda Condition: UDAVARTINI,

Registration Number: CTRI/2025/06/089243

Lead Sponsor: C.S.M.S.S Ayurved Mahavidyalaya and Rugnalaya Kanchanwadi Aurangabad India 431001

Brief Summary: In Ayurvedic classics Gynaecological disorders have been described under caption Yonivyapad. Among them Udavartini Yonivypad given by Acharya Charak is closely related to the symptoms of Primary Dysmenorrhea. Here Vata vitiated by vegadharana pushes the menstrual blood upward and then expel it out with difficulty leading to pain. Pain will relieve by itself once the menstrual flow starts, which itself indicate the spasmodic nature of pain. Acharya Sushrut said such symptoms in Udavarta Yonivyapad, the women eliminates frothy menstrual blood with difficulty. Acharya Vagbhat also mentioned Vata aggravated by suppression of the urges, torments the vagina and expels frothy menstrual blood with difficulty. All classical Samhitas like Charak Samhita, Sushrut Samhita, Vagbhat Samhita have mentioned Udavartini/Udavarta/ Udavritta Yonivyapad respectively as Vataj Yonivyapad. So Vatanulomak and Vatashamak dravyas have main role in treatment. Kulatthadi Kashay is one among lots of herbal preparation which has indication in Udavarta and shul.

Prevalence of Dysmenorrhea in India is 70.2%. Majority of subjects experienced pain for 1-2 days during menstruation. 23.2% girls experienced pain for 2-3 days during menstruation. It is responsible for highest incidence of absenteeism resulting in loss of work hours and economic loss. Hence these females are forced to take antispasmodic, analgesics, prostaglandin synthetase inhibitors etc. during menstruation. However Prostaglandin synthetase inhibitors are contraindicated in women with gastrointestinal ulcer and bronchial asthma. Side effects includes nausea, vomiting, blurred vision,

nephrotoxicity and gastric ulcer on prolong use.

Previous studies on Udavartini Yonivyapad primarily focused on various types of Basti, and there are very few studies on oral medication. This reveals the necessity of alternate treatment to tackle this situation with suitable remedies. Kulatthadi Kashay mentioned in Sahasrayoga containing drugs which are Kulattha, Lahsun, Erand, Patha, Granthik, Nagar and Yavkshar having properties of Dipan, Pachan, Anuloman and Vedanashaman. Previously no research was done on Kulatthadi Kashay, considering above facts it is selected for study.

Study will be conducted on 100 diagnosed patients of Udavartini Yonivyapad. Written consent will be taken. Initial assessment will be done. Patient treated with interventional group Kulatthadi Kashay and control group Shatapushpa Churna. Patients will be assessed at follow ups. Observation and Results will be noted and Statistical Analysis, Discussion and Conclusion will be drawn.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 100

Inclusion Criteria

Diagnosed patients of Udavartini Yonivyapad of age group from 10 to 24 years young unmarried patient.
Patient having chief complaints of painful menstruation with associated symptoms without any pelvic pathology.

Exclusion Criteria

Patients of age group below 10 & above 24 years married patients.
Patients of pelvic pathology i.e. PID, PCOD, Cervical stenosis, Fibroid, Endometriosis, DUB, Adenomyosis, Endometrial polyp.
Patient taking any hormonal therapy.
Patient with congenital anomalies of reproductive system.
Menorrhagia.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Lakshanas of Udavartini Yonivyapad will decrease	Baseline-30th, 60th day

Secondary Outcome Measures

Name	Time	Method
1.Study Udavartini yonivyapad according to	Ayurveda.

Trial Locations

Locations (1): C.S.M.S.S Ayurved Mahavidyalaya, Aurangabad
🇮🇳
Aurangabad, MAHARASHTRA, India
C.S.M.S.S Ayurved Mahavidyalaya, Aurangabad
🇮🇳Aurangabad, MAHARASHTRA, India
Dr Sameeksha Chandrashekhar Charpe
Principal investigator
7709558572
charpes98@gmail.com