Prognostic Factors for Descending Necrotizing Mediastinitis Development in Deep Space Neck Infections - A Retrospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 289
- 主要终点
- Incidence of mediastinitis
研究概览
简要总结
Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections.
详细描述
Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections. The study enrolled patients admitted to the Emergency Center of Vojvodina with the diagnosis of multispace DNI with or without DNM either as the primary diagnosis or with discharged diagnosis after surgical treatment during 7-years period. The data were obtained from patient medical records.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients admitted to the hospital due to deep neck infection affecting two or more spaces with or without descending necrotizing medioastinitis
- •complete diagnosis and treatment data available from medical charts
排除标准
- •incomplete medical data
- •infection confined to one deep neck space
- •patients treated under local anesthesia
- •patients with superficial skin infections
- •iatrogenic infections
- •infected tumors
结局指标
主要结局
Incidence of mediastinitis
时间窗: Within 6 hours of admission
Neck and chest computed tomography (CT)
次要结局
- Average number of hospital days(Through study completion, an average of one month)
- Number of infected deep neck spaces(Within 6 hours of admission)
- Microbiological findings in DNI and DNM(Within 1 week of admission)
- Incidence of complications(Within 30 days from admission)
研究者
Denis Brajković
Principal Investigator
Clinical Center of Vojvodina