ISRCTN11358769招募中未知
The effects of Prebiotic Supplementation on Quality of Life, Control of Asthma, and Markers of Systemic Inflammation in Adults with Asthma. A Double-Blind, Placebo-Controlled, Crossover Trial.
ottingham Trent University0 个研究点目标入组 14 人开始时间: 2019年4月4日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 14
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1.18-50 years of age at the date of your first visit.
- •2. Body mass index (BMI) of 18.5-25 kg·m2 (we can work this out for you using your height and body weight).
- •3. Non-smoker.
- •4. Asthma is defined as Steps 1 to 4 based on British Thoracic Society guidelines.
- •5. On a stable asthma treatment for 3 months
- •6. Current medication prescription from your GP if diagnosed with asthma (e.g. maintenance and reliever inhalers).
- •7. Be able and willing to follow all trial requirements.
- •8. Disclose any nutritional supplements you take to the researcher, to determine whether these may be considered as ‘exclusion criteria’.
排除标准
- •1. Suffer from asthma but do not have a current medication prescription from your GP (e.g. maintenance and reliever inhalers).
- •2. Regularly consume Omega-3 supplements, and/or eat high levels of Omega-3 (e.g. more than 1-2 portions of oily fish such as salmon or mackerel a week).
- •3. Take aspirin or other non-steroidal anti-inflammatory drugs such as ibuprofen once a day on 5 of of the 7 days of the week.
- •4. Pregnant or planning a pregnancy during the time of the study (on each visit you will be asked to complete a pregnancy test if you are within childbearing age).
- •5. Consumed prebiotics and/or probiotics (supplements), drugs that affect gastrointestinal mobility or laxatives in the 4 weeks before signing the consent form.
- •6. Daily dose of anti-histamine, which you could not temporarily avoid for 72 hours before each testing session without exacerbation of symptoms.
- •7. Vegetarian or vegan diet.
- •8. Previously diagnosed with chronic obstructive pulmonary disease (COPD), emphysema, chronic bronchitis, or similar respiratory (breathing-related) illness.
- •9. Admitted to hospital during the past 12 months for your asthma.
- •10. History of heart failure, pulmonary hypertension, embolism, or other pulmonary heart disease.
- •11. History of recurrent chest infections.
- •12. Acute infection in the last four weeks, and/or major operation in the past four months.
- •13. History of gastrointestinal drug reaction.
- •14. Taken antibiotics in the past 3 months.
- •15. History or current evidence of gastrointestinal disease (e.g. chronic constipation, diarrhoea, irritable bowel syndrome, Chrohn’s disease).
- •16. Recently taken part in other research projects. Please notify the chief investigator.
- •17. Lactose intolerant.
- •18. Regularly take antioxidant supplements, such as beta-carotene, vitamin A, vitamin C, vitamin E, lutein and selenium. Standard multivitamin and mineral supplements are acceptable; however, If a single antioxidant supplement (e.g. Vitamin C), is more than the recommended daily DRV’s this must be checked with the chief investigator.
研究者
相似试验
进行中（未招募）
不适用
The effect of prebiotic supplementation on asthmaAsthmaISRCTN14120894ottingham Trent University15
尚未招募
不适用
Dietary prebiotic supplementation in adults with prediabetesPre-diabetestype 2 diabetesMetabolic and Endocrine - DiabetesDiet and Nutrition - Other diet and nutrition disordersACTRN12613000130763Monash University40
已完成
不适用
Effects of probiotic and prebiotic supplements in patients with major depressive disorderCondition 1: major depressive disoreders. Condition 2: Mild depression. Condition 3: Moderate depression.Depressive episodeMild depressive episodeModerate depressive episodeIRCT2015092924271N1Tehran University of Medical Sciences90
招募中
2 期
Effects of supplementation with beneficial bacteria on quality of life, inflammatory profile, eating behavior, metabolism and nutritional status of patients after stomach reduction surgerydysbiosisgastric bypassObesityRBR-4x3gqpniversidade Federal do Paraná
已完成
不适用
Effects of prebiotic and probiotic supplementation on Weight Loss, psychological profile and metabolic parameters in obese subjectsPACTR20221070599879545