Analysis of Passive Leg Raise Test on Blood Pressure in Critically Ill Patients.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Correlation of SVV with increase in blood pressure
研究概览
简要总结
Positioning intensive care patients in Trendelenburg position to identify fluid responsiveness assessed by PiCCO device.
详细描述
It is a prospective observational study. Patients admitted to Intensive Care Unit of University Clinical Centre of Gdańsk, receiving advanced hemodynamic monitoring with PiCCO method will be enrolled. After blood pressure measurement, PiCCO will be calibrated with transpulmonary thermodilution with 10 - 20 ml of cold saline. Readings will be noted. The patient will be positioned in Trendelenburg position with it's head 15 degrees down. The increase of blood pressure after positioning in relation to the values obtained before the trial will be correlated to the parameters that asses patent's volaemia. After 5 minutes patient will be back to supine position and hemodynamic parameters will be recorded for another 5 minute.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hemodynamic instability
- •mechanical ventilation
排除标准
- •increased intracranial pressure
- •increased intraabdominal pressure
- •lower limbs sequential compression system
- •agitation
- •patients exposed to pain stimulus before the test
- •aortic aneurysm
- •left to right cardiac shunt
- •severe valvular insufficiency
结局指标
主要结局
Correlation of SVV with increase in blood pressure
时间窗: 10 minutes
Stroke volume variation (SVV) is a validated parameter that assess fluid responsiveness. In patients in whom SVV value is higher, theoretically Trendelenburg position will increase blood pressure in greater degree, than in patients in whom SVV is lower. We want to identify whether such correlation exist.
次要结局
未报告次要终点